OPTIMAL DURATION OF NEOADJUVANT TAXANE AND CARBOPLATIN COMBINED WITH ANTI-HER2 TARGETED THERAPY FOR HER2-POSITIVE BREAST CANCER

Optimal Duration of Neoadjuvant Taxane and Carboplatin Combined With Anti-HER2 Targeted Therapy for HER2-Positive Breast Cancer

BackgroundTaxane, carboplatin and trastuzumab (TCH) is an effective neoadjuvant regimen for human epidermal growth factor Number Holders receptor 2 (HER2)-positive breast cancer with high pathologic complete response (pCR) rate.The KATHERINE trial changes the outlook for high-risk HER2-positive breast cancer, which suggests that escalation treatmen

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On the Relationship of Cold Pool and Bulk Shear Magnitudes on Upscale Convective Growth in the Great Plains of the United States

Upscale convective growth remains a poorly understood aspect of convective evolution, and numerical weather prediction models struggle to accurately depict convective morphology.To better understand some physical mechanisms encouraging upscale growth, 30 warm-season convective events from 2016 over the United States Great Plains were simulated usin

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